Roma have won four matches on the spin and can consolidate their place at the top of Serie A with a victory over poor travellers Napoli, who have lost five of their last six away games across all competitions.

After a goalless first leg, Cruz Azul can make home advantage count when they entertain Guadalajara. Cruz Azul have won seven of their last nine home games and are facing a side who lost three of their eight trips in the regular season. Cruz Azul are also unbeaten in four against Guadalajara (W3, D1).

Birmingham are one point ahead of Watford and they’ve beaten Norwich, Millwall, and Portsmouth across their last three at home, scoring 12 times. Watford have only managed one clean sheet in 17 league games, while they have one away win to their name this term. The Blues have gone three games without a clean sheet, however, so the visitors can at least grab a consolation effort.